PDO refers to polydioxanone, a polymer used in medical sutures. In a thread lift procedure, PDO threads are placed just beneath the surface of the skin with a cannula, the same flexible tool used to inject filler. The introduction of the threads to the skin causes neocollagenesis production in the area which leads to increased volume and firmness over time.   PDO threads have a high safety profile, complete absorption and minimal tissue reaction. The PDO thread generates tensing fibrosis in the surrounding tissue. The risk for scarring is absent when inserted correctly.   The effects of a thread lift are visible immediately and improve over several months. Results are not permanent but can last for up to two years. Downtime is minimal with PDO thread treatment and produces even better results when combined with other volumizing procedures.